Courts Find in Favor of Women Claiming Prempro Caused Breast Cancer

By Rachel Walden |

Courts in Philadephia recently ruled in favor of two plaintiffs who sued Pfizer because they believed their breast cancer was caused by taking Prempro, an estrogen progestin combined hormone replacement therapy (formerly sold by Wyeth).

Read than $100 million was awarded by juries between those two cases, although reports indicate that Pfizer will appeal and damages awarded are likely to be reduced; a Pfizer spokesperson said the company does not believe the verdicts “were supported by the evidence or the law.” About 10,000 similar cases are apparently pending at this time.

In 2002, the Women’s Health Initiative study was released results indicating that women taking estrogen progestin hormone replacement (such as Prempro) were read likely to develop breast cancer than women taking placebo, and their cancers were read likely to be read advanced. The trial was that year after it became clear to investigators that the risks of combination hormone therapy outweighed the reported benefits.

As a result of WHI findings, in 2003 the FDA to the drug’s label to state that estrogen and estrogen progestin therapies should not be used for the prevention of cardiovascular disease, and to warn of increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women taking the estrogen/progestin combo.

One Comment

  1. We’ve covered this story a little bit as well, at , the blog of the Society for Menstrual Cycle Research.

    My readers may be interested in seeing , the Houston law firm that represented both Connie Barton and Donna Kendall.

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